Publications

2017

  • Bangalore S, Edelman ER, Bhatt DL. First Generation Bioresorbable Vascular Scaffolds: Disappearing Stents or Disappearing Evidence? Journal of the American College of Cardiology. DOI: 10.1016/j/jacc.2017.04.012. PubMed: 28412390
  • Williams D, Edelman ER, Radisic M, Laurencin C, Untereker D. Engagement of the Medical-technology Sector with Society. Science Translational Medicine, 12 Apr 2017:Vol. 9, Issue 385, DOI: 10.1126. PubMed: 28404862
  • O’Rourke MF, Adji A, Nicols WW, Vlachopoulos C, Edelman ER. Application of Arterial Hemodynamics to Clinical Practice: A Testament to Medical Science in London. Artery Research, in press available online 18 April 2017. https://doi.org/10.1016/j.artres.2017.03.003
  • Abraham E, Gadish O, Franses JW, Chitalia VC, Artzi, N, Edelman ER, Matrix-Embedded Endothelial Cells Attain a Progenitor-Like Phenotype. Advanced Biosystems, 20 July 2017, DOI: 10.1002/adbi.201700057
  • Kandzari DE, Pieter C. Smits PC, Love MP, Ben-Yehuda O, Banai S, Robinson SD, Jonas M, Kornowski R, Bagur R, Iniguez A, Danenberg HD, Feldman RL, Jauhar R, Chandna H, Parikh MA, Perlman GY, Balcells M, Markham PM, Ozan MO, Genereux P, Edelman E, Leon MB, Stone GW. Randomized Comparison of Ridaforolimus-Eluting and Zotarolimus-Eluting Coronary Stents in Patients with Coronary Artery Disease: Primary Results from the Bionics Trial; Circulation. 2017;136:1304-1314. Originally published August 9, 2017. doi: 10.1161/CIRCULATIONAHA.117.028885 PMID: 28794001
  • Conway C, McGarry JP, Edelman ER, McHugh PE. Numerical Simulation of Stent Angioplasty with Predilation: An Investigation into Lesion Constitutive Representation and Calcification Influence. Cover Annals of Biomedical Engineering 2017 Sept; 45(9):2244-2252. Online 05/09/2017 .https://doi.org/10.1007/s10439-017-1851-3. PMID: 28488215
  • Tzafriri AR, Garcia-Polite F, Zani B, Stanley J, Muraj B, Knutson J, Kohler R, Markham P, Nikanorov A, Edelman ER. Calcified Plaque Modification Alters Local Drug Delivery in the Treatment of Peripheral Atherosclerosis. Journal of Controlled Release 264 (2017) 203–210. Online 09/01/17. http://dx.doi.org/10.1016/j.jconrel.2017.08.037
  • Amrute JM, Anthanasiou LS, Rikhtegar F, de la Torre Hernández JM, Camarer TM, Edelman ER. Automated Segmentation of Bioabsorbable Stent Struts in Intracoronary Optical Coherence Tomography Images. J Biomed Optics 2017 available on line in advance of print.
  • Karanasiou G, Tachos N, Sakellarios A, Conway C, Michalis L, Edelman ER and Fotiadis D. In silico assessment of the effects of material on stent deployment. 17th annual IEEE International Conference on Bioinformatics and Biogengineering (BIBE 2017, http://bibe2017.com) October 23-25, Journal of Biomed Optics 2017 available on line in advance of print.
  • Shashar M, Belghasem M, Matsuura S, Walker J, Richards S, Alousi F, Rijal K, Kolachalama V, Balcells M, Odagi M, Nagasawa K, Henderson J, Gautam A, Rushmore R, Francis J, Kirchhofer D, Kolandaivelu K, Sherr D, Edelman ER, Ravid K, Chitalia V. Targeting STUB1 tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk. Accepted for publication in Science Translational Medicine. October 2017

2016

  • Kumaran Kolandaivelu and Farhad Rikhtegar, The Systems Biocompatibility of Coronary Stenting. Interventional Cardiology Clinics 5 (3), 295-306, 2016
  • Ewen S, Ukena C, Luscher TF, Bergmann M, Blankestijn PJ, Blessing E, Cremers B, Dorr O, Hering D, Kaiser L, Nef H, Noory E, Schlaich M, Sharif F, Sudano I, Vogel B, Voskuil M, Zeller T, Tzafriri A, Edelman ER, Lauder L, Scheller B, Bohm M, Mahfoud F. Anatomical and procedural determinants of catheter-base renal denervation.  Cardiovasc Revasc Med. 2016 Oct – Nov;17(7):474-479. doi: 10.1016/j.carrev.2016.08.004. PubMed PMID: 27617388
  • Garcia-Polite F, Martorell J, Del-Rey-Puech P, Melgar-Lesmes P, O’Brien C, Roquer J, Ois A, Principe A, Edelman ER,  Balcells M.  Pulsatility and high shear stress deteriorate barrier phenotype in brain microvascular endothelium. J Cereb Blood Flow Metab. 2016 Oct 4. pii: 0271678X16672482. [Epub ahead of print] PubMed PMID: 27702879
  • Andreou Y, Shishido K, Antoniadis AP, Takahashi S, Tsuda M, Papafaklis MI, Saito S, Coskun AU, Feldman CL, Edelman ER, Stone PH. Atherosclerotic plaque behind the stent changes after bare-metal and drug-eluting stent implantation in humans: Implications for late stent failure? Atherosclerosis (2016), doi: 10.1016/j.atherosclerosis.2016.07.914 PMCID: PMC5035643.
  • Rikhtegar F, Edelman ER, Olgac U, Poulikakos, Kurtcuoglu, V.  Drug Deposition in Coronary Arteries with Overlapping Drug-eluting Stents.  Journal of Controlled Release.  doi:10.1016/j.jconrel.2016.07.023 Volume 238, 1-9, PMCID: PMC5014575
  • Keshavarz-Motamed Z, Rikhtegar F, Partida R, Nakamura K, Staziaki P, Ben-Assa E, Ghoshhajra B, Bhatt A, Edelman ER. Elimination of Trans-coarctation Pressure Gradients Has No Impact on Left Ventricular Function or Aortic Shear Stress Post Intervention in Patients with Mild Coarctation. JACC: Cardiovascular Intervention 2016;9(18):1953-1965. doi:10.1016/j.jcin.2016.06.054. PMID: 27659574
  • O’Brien, CC, Lopes AC, Kolandaivelu K. Kunio M, Brown J, Kolachalama, VB, Conway, C, Bailey L, Makham P, Costa M, Ware J, Edelman ER.  Vascular Response to Experimental Stent Malapposition and Under-Expansion.  Annals of Biomedical Engineering. June 6, 2016.  44(7), 2251-2260 PMID: 26732391 PMCID: 4893976.
  • Indolfi L, Ligorio M, Ting D, Xega K , Tzafriri A, Bersani F, Aceto N, Thapar V, Fuchs B, Deshpande V, Baker A, Ferrone C, Haber D, Langer R, Clark V, Edelman ER. A Tunable Delivery Platform to Provide Local Chemotherapy for Pancreatic Ductal Adenocarcinoma. Biomaterials. doi:10.1016/j.biomaterials.2016.03.044. PMCID: PMC4849535
  • Faucher KM, Artzi N. Beck M, Beckerman R, Moodie G, Albergo T, Conroy S, Dale A, Corbeil S, Martakos P, Edelman ER. Tracking of Drug Release and Material Fate for Naturally Derived Omega-3 Fatty Acid Biomaterials. Annals of Biomedical Engineering, March 2016 44(3) 782-792 PMID 26502170; 10.1007/s 10439-015-1489-ywilliam
  • O’Brien CC, Kolandaivelu K, Brown J, Lopes AC, Kunio M, Kolachalama VB, Edelman ER. Constraining OCT With Knowledge Of Device Design Enables High Accuracy Hemodynamic Assessment Of Endovascular Implants PLOS ONE. 11(2):e0149178.  February 23, 2016. PMID: 26906566. PMCID: 4764338
  • Lansky AJ, Kastrati A, Edelman ER, Parise H, Ng VG, Ormiston J, Wijns W, Byrne RA. Comparison of the Absorbable Polymer Sirolimus-Eluting Stent (MiStent) to the Durable Polymer Everolimus-Eluting Stent (Xience) (from the DESSOLVE I/II and ISAR-TEST-4 Studies), Am. J. Cardiol. February 15 2016; 117(4): 532-538. PMID: 26762729
  • Melgar-Lesmes P, Garcia-Polite F, Del-Rey Puech P, Rosas E, Dreyfuss JL, Montell E, Verges J, Edelman ER, Verges J, Balcells M.  Treatment with chondroitin sulfate to modulate inflammation and atherogenesis in obesity. Atherosclerosis. 2016 Feb;245:82-7. doi: 10.1016/j.atherosclerosis.2015.12.016.. PMID: 26714044  PMCID: PMC4738029.
  • Melgar-Lesmes P, Balcells-Camp M, Edelman ER, Implantation of healthy matrix-embedded endothelial cells rescues dysfunctional endothelium and ischemic tissue in liver engraftment, Gut, February 5, 2016. pii: gutjnl-2015-310409. doi: 10.1136/gutjnl-2015-310409.  PMID: 26851165. PMCID: PMC5288307
  • Everett, K., C. Conway, G. Desany, B. Baker, G. Choi, C. Taylor, and E. Edelman, Structural Mechanics Predictions Relating to Clinical Coronary Stent Fracture in a 5 Year Period in FDA MAUDE Database. Ann Biomed Eng, on line 10/14/2015. Vol 44 No.2 February 2016 pp 391-403   PMID: 26467552. PMCID: PMC 5082979
  • Artzi N, Tzafriri AR, Faucher KM, Moodie G, Albergo T, Conroy S, Corbeil S, Martako P, Virmani R, Edelman ER. Sustained Efficacy and Arterial Drug Retention by a Fast Drug Eluting Cross-Linked Fatty Acid Coronary Stent Coating, Annals of Biomedical Eng., Vol 44, No2, February 2016DOI: 10.1007/s10439-015-1435-z.  epublished ahead of print August 18, 2015. PMID: 26314990. PMCID: PMC4767594

2015

  • Hara T, Ughi G, McCarthy JR, Erdem SS, Mauskapf A, Lyon SC, Fard AM, Edelman ER, Tearney GJ, Jaffer FA . Intravascular Fibrin Molecular Imaging Improves the Detection of Unhealed Stents Assessed by Optical Coherence Tomography In Vivo. European Heart Journal. EUROHEARTJD. December 18, 2015. Pii: ehv677 PMID: 26685129
  • Connor Y, Tekleab S, Nandakumar S, Walls C, Tekleab Y, Husain A, Gadish O, Sabbisetti V, Kaushik S, Sehrawat S, Kulkarni A, Dvorak H, Edelman ER, Zetter B, Sengupta S. Physical nanoscale conduits-mediated communication between tumor cells and endothelium enables a metastatic hijack. Nature Communications 6 Article number 8671, doi:10.1038/nc commns9671. December 16, 2015.  PMID: 26669454. PMCID: PMC4697439.
  • Keshavarz-Motamed Z, Edelman ER, Motamed PK, Garcia J, Dahdah N, Kadem L. The role of aortic compliance in determination of coarctation severity: lumped parameter modeling, in vitro study and clinical evaluation. Journal of Biomechanics, December 16, 2015, 48(16): 4229-37.  PMID: 26596718.  PMCID: PMC4690767
  • Unterman S, Freiman A, Beckerman M, Abraham E, Levy E, Artzi N, Edelman ER  Tuning of Collagen Scaffold Properties Modulates Embedded Endothelial Cell Regulatory Phenotype in Repair of Vascular Injuries in vivo.  Advanced Healthcare Materials. November 2015 Vol(4), Issue 15, 2220-2228.  PMID 26333178. PMCID:  PMC4664078
  • Melgar-Lesmes P, Edelman ER. Monocyte-endothelial cell interactions in the regulation of vascular sprouting and liver regeneration in mouse. J Hepatol. 2015 May 25. PMID: 26022689. PMCID: PMC4575901
  • Conde, J., C. Bao, Y. Tan, D. Cui, E.R. Edelman, H.S. Azevedo, H.J. Byrne, N. Artzi and F. Tian. Dual targeted immunotherapy via in vivo delivery of biohybrid RNAi-peptide nanoparticles to tumour-associated macrophages and cancer cells. Advanced Functional Materials, July 15, 2015: 4183-4194. COVER Featured PMCID: PMC4914053
  • Keshavarz-Motamed Z, Edelman ER, Motamed PK, Garcia J, Dahdah N, Kadem L. The role of aortic compliance in determination of coarctation severity: lumped parameter modeling, in vitro study and clinical evaluation. J Biomech. 2015, 48(16): 4229-4237.
  • Vijayaratnam PR, O’Brien CC, Reizes JA, Barber TJ, Edelman ER.The Impact of Blood Rheology on Drug Transport in Stented Arteries: Steady Simulations.PLoS One. 2015 Jun 12;10(6)
  • Melgar-Lesmes P, Edelman ER. Monocyte-endothelial cell interactions in the regulation of vascular sprouting and liver regeneration in mouse. J Hepatol. 2015 May 25.
  • Shivanna S, Kolandaivelu K, Shashar M, Belghasim M, Al-Rabadi L, Balcells M, Zhang A, Weinberg J, Francis J, Pollastri MP, Edelman ER, Sherr DH, Chitalia VC. The Aryl Hydrocarbon Receptor is a Critical Regulator of Tissue Factor Stability and an Antithrombotic Target in Uremia. J Am Soc Nephrol. 2015 May 27
  • Tzafriri AR, Keating JH, Markham PM, Spognardi AM, Stanley JR, Wong G, Zani BG, Highsmith D, O’Fallon P, Fuimaono K, Mahfoud F, Edelman ER.Arterial microanatomy determines the success of energy-based renal denervation in controlling hypertension.Sci Transl Med. 2015 Apr 29;7(285)
  • Conde,J., E.R. Edelman, N. Artzi. Target-responsive DNA/RNA nanomaterials for microRNA sensing and inhibition: The jack-of-all-trades in cancer nanotheranostics? Advanced Drug Delivery Reviews, 81, 169-183, 2015.
  • Conde, J., C. Bao, Y. Tan, D. Cui, E.R. Edelman, H.S. Azevedo, H.J. Byrne, N. Artzi and F. Tian. Dual targeted immunotherapy via in vivo delivery of biohybrid RNAi-peptide nanoparticles to tumour-associated macrophages and cancer cells. Advanced Functional Materials, 2015. COVER Featured
  • Zani BG, Baird R, Stanley JR, Markham PM, Wilke M, Zeiter S, Beck A, Nehrbass D, Kopia GA, Edelman ER, Rabiner R. Evaluation of an intramedullary bone stabilization system using a light-curable monomer in sheep. J Biomed Mater Res B Appl Biomater. 2015 Mar 12
  • Andreou I, Sun X, Stone PH, Edelman ER, Feinberg MW. miRNAs in atherosclerotic plaque initiation, progression, and rupture. Trends Mol Med. 2015 May;21(5):307-18.
  • Andreou I, Antoniadis AP, Shishido K, Papafaklis MI, Koskinas KC, Chatzizisis YS, Coskun AU, Edelman ER, Feldman CL, Stone PH.How do we prevent the vulnerable atherosclerotic plaque from rupturing? Insights from in vivo assessments of plaque, vascular remodeling, and local endothelial shear stress.J Cardiovasc Pharmacol Ther. 2015 May;20(3):261-75.
  • Stanley JR, Tzafriri AR, Regan K, LaRochelle A, Wong G, Zani BG, Markham PM, Bailey L, Spognardi A, Kopia GA, Edelman ER.Particulates from hydrophilic-coated guiding sheaths embolise to the brain. EuroIntervention. 2015 Mar 5;10(12)
  • Kolandaivelu K, O’Brien CC, Shazly T, Edelman ER, Kolachalama VB. Enhancing physiologic simulations using supervised learning on coarse mesh solutions. J R Soc Interface. 2015 Mar 6;12(104)
  • Verheye S, Jolicœur EM, Behan MW, Pettersson T, Sainsbury P, Hill J, Vrolix M, Agostoni P, Engstrom T, Labinaz M, de Silva R, Schwartz M, Meyten N, Uren NG, Doucet S, Tanguay JF, Lindsay S, Henry TD, White CJ, Edelman ER, Banai S. Efficacy of a device to narrow the coronary sinus in refractory angina. N Engl J Med. 2015 Feb 5;372(6):519-27
  • Oliva N, Carcole M, Beckerman M, Seliktar S, Hayward A, Stanley J, Parry NM, Edelman ER, Artzi N. Regulation of dendrimer/dextran material performance by altered tissue microenvironment in inflammation and neoplasia.Sci Transl Med. 2015 Jan 28;7(272)
  • Chan KE, Edelman ER, Wenger JB, Thadhani RI, Maddux FW. Dabigatran and rivaroxaban use in atrial fibrillation patients on hemodialysis. Circulation. 2015 Mar 17;131(11):972-9
  • Maslov MM, Wei AE, Pezone MJ, Edelman ER, Lovich MA. Vascular Dilation, Tachycardia, and Increased Inotropy Occur Sequentially with Increasing Epinephrine Dose Rate, Plasma and Myocardial Concentrations, and cAMP, Heart, Lung and Circulation 2015

2014

  • Tzafriri AR, Mahfoud F, Keating JH, Markham PM, Spognardi A, Wong G, Fuimaono K, Böhm M, Edelman ER.Innervation patterns may limit response to endovascular renal denervation.J Am Coll Cardiol. 2014 Sep 16;64(11):1079-87.
  • Mariani J Jr, Guedes C, Soares P, Zalc S, Campos CM, Lopes AC, Spadaro AG, Perin MA, Filho AE, Takimura CK, Ribeiro E, Kalil-Filho R, Edelman ER, Serruys PW, Lemos PA. Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.JACC Cardiovasc Interv. 2014 Nov;7(11):1287-93.
  • Sakakura K, Ladich E, Edelman ER, Markham P, Stanley JR, Keating J, Kolodgie FD, Virmani R, Joner M.Methodological standardization for the pre-clinical evaluation of renal sympathetic denervation.JACC Cardiovasc Interv. 2014 Oct;7(10):1184-93.
  • Maslov MY, Edelman ER, Pezone MJ, Wei AE, Wakim MG, Murray MR, Tsukada H, Gerogiannis IS, Groothuis A, Lovich MA.Myocardial drug distribution generated from local epicardial application: potential impact of cardiac capillary perfusion in a swine model using epinephrine. J Control Release. 2014 Nov 28;194:257-65.
  • Martorell J, Santomá P, Kolandaivelu K, Kolachalama VB, Melgar-Lesmes P, Molins JJ, García L, Edelman ER, Balcells M. Extent of flow recirculation governs expression of atherosclerotic and thrombotic biomarkers in arterial bifurcations. Cardiovasc Res. 2014 Jul 1;103(1):37-46
  • Gadish O, Edelman ER. Chapter 14: Paracrine regulation from tissue engineered constructs. Atala A, Allickson JG, editors. Translational Regenerative Medicine. Elsevier Academic Press 2014
  • Kolandaivelu, K., B.B. Leiden, and E.R. Edelman, Predicting response to endovascular therapies: Dissecting the roles of local lesion complexity, systemic comorbidity, and clinical uncertainty. J Biomech, 2014 Mar 3;47(4): p. 908-21. [e-pub]
  • Banai, S., S. Verheye, A. Cheung, M. Schwartz, A. Marko, R. Lane, E.M. Jolicoeur, P. Garceau, S. Biner, J.F. Tanguay, E.R. Edelman, and C.J. White, Transapical mitral implantation of the tiara bioprosthesis: pre-clinical results. JACC Cardiovasc Interv, 2014 Feb 7;(2):154-62. [e-pub]
  • Turjman, A.S., F. Turjman, and E.R. Edelman, Role of fluid dynamics and inflammation in intracranial aneurysm formation. Circulation, 2014 Jan 21;129(3):373-82. [e-pub]

2013

  • Nickmann M, Saemisch M, Wilbert-Lampen U, Nickel T, Edelman ER, Methe H. Cell matrix contact modifies endothelial major histocompatibility complex class II expression in high-glucose environment. American Journal Physiol Heart Circ Physiol; 2013 December 1;305(11):H1592-9. [e-pub]
  • Koskinas KC, Chatzizisis YS, Papafaklis M, Coskun AU, Baker AB, Jarolim P, Antoniadis A, Edelman ER, Stone P, Feldman C:Synergistic Effect of Local Endothelial Shear Stress and Systemic Hypercholesterolemia on Coronary Atherosclerotic Plaque Progression and Composition in Pigs. International Journal of Cardiology, 2013 Nov 30; 169(6):394-401 [e-pub]
  • Maslov MY, Edelman ER, Wei AE, Pezone MJ, Lovich MA.  High concentrations of drug in target tissues following local controlled release are utilized for both drug distribution and biological effect: an example with epicardial inotropic drug delivery. Journal of Control Release; 2013 October 28; 171(2):201-7. [e-pub]
  • Franses, J.W., N.C. Drosu, W.J. Gibson, V.C. Chitalia, and E.R. Edelman, Dysfunctional endothelial cells directly stimulate cancer inflammation and metastasis. Int J Cancer, 2013 Sep 15;133(6):1334-44. [e-pub]
  • Rosàs E, Santomá P, Duran-Frigola M, Hernandez B, Llinàs MC, Ruiz-González R, Nonell S, Sánchez-García D, Edelman ER, Balcells M. Modifications of microvascular EC surface modulate phototoxicity of a porphycene anti-ICAM-1 immunoconjugate; therapeutic implications. Langmuir. 2013 Aug 6;29(31):9734-43.[e-pub]
  • Koskinask KC, Sukhova G, Baker AB, Papafaklis M; Chatzizisis Y, Coskun A, Quillard T, Oskinas K, Maynard C, Antonia A, Shi G, Libby P, Edelman ER, Feldman, C, Stone, P: Thin-capped atheromata with reduced collagen content in pigs develop in coronary arterial regions exposed to persistently low endothelial shear stress. Arterioscler Throm Vasc Biol, 2013 Jul;33(7):1494-1504. [e-pub]
  • O’Brien, C.C., V.B. Kolachalama, T.J. Barber, A. Simmons, and E.R. Edelman, Impact of flow pulsatility on arterial drug distribution in stent-based therapy. J Control Release. 2013 Jun 10;168(2):115-24. [e-pub]
  • Kolachalama, V.B., S.D. Pacetti, J.W. Franses, J.J. Stankus, H.Q. Zhao, T. Shazly, A. Nikanorov, L.B. Schwartz, A.R. Tzafriri, and E.R. Edelman, Mechanisms of tissue uptake and retention in zotarolimus-coated balloon therapy. Circulation, 2013 May 21;127(20):2047-55. [e-pub]
  • O’Brien CC, Kolachalama VB, Barber TJ, Simmons A, Edelman ER. Impact of flow pulsatility on arterial drug distribution in stent-based therapyJournal of Controlled Release. 2013 Mar 27;168(2):115-124.[e-pub]
  • Franses JW, Drosu NC, Gibson WJ, Chitalia VC, Edelman ER. Dysfunctional endothelial cells directly stimulate cancer inflammation and metastasis. International Journal of Cancer. 2013 Mar 5.  [e-pub]
  • Orekhov, A.N., I.A. Sobenin, N.V. Korneev, T.V. Kirichenko, V.A. Myasoedova, A.A. Melnichenko, M. Balcells, E.R. Edelman, and Y.V. Bobryshev. Anti-atherosclerotic therapy based on botanicals. Recent Pat Cardiovasc Drug Discov, 2013 Apr;8(1):56-66. [e-pub]
  • Rosas E, Sobenin I, Orekhov A, Edelman ER, Balcells M. Importance of Receptor-Targeted Systems In The Battle Against AtherosclerosisCurrent Pharmaceutical Design.  2013 Feb 15;19(33):5897-903. [e-pub]
  • Jolicur ME, Banai S, Henry DT, Schwartz M, Doucet S, White JC, Edelman ER, Verheye S: A phase II, sham-controlled, double-blinded study testing the safety and efficacy of the coronary sinus reducer in patients with refractory angina: study protocol for a randomized controlled trial. Trials. 2013 Feb 15;14:46. [e-pub]
  • Banai S, Finkelstein A, Almagor Y, Assali A, Hasin Y, Rosenschein U, Apruzzese P, Lansky AJ, Kume T, Edelman ER. Targeted anti-inflammatory systemic therapy for restenosis: the Biorest Liposomal Alendronate with Stenting sTudy (BLAST)-a double blind, randomized clinical trialAmerican Heart Journal. 2013 Feb;165(2):234-40.e1. [e-pub]
  • Chitalia VC, Shivanna S, Martorell J, Balcells M, Bosch I, Kolandaivelu K, Edelman ER. Uremic serum and solutes increase post-vascular interventional thrombotic risk through altered stability of smooth muscle cell tissue factorCirculation. 2013 Jan 22;127(3):365-76. [e-pub].
  • Murikipudi, S., H. Methe, and E.R. Edelman, The effect of substrate modulus on the growth and function of matrix-embedded endothelial cells. Biomaterials, 2013 Jan;34(3):677-84. [e-pub]
  • Tzafriri AR, Edelman ER. Y.H. Bae et al. (eds.), Cancer Targeted Drug Delivery: An Elusive Dream, DOI 10.1007/978-1-4614-7876-8_21, Springer Science+Business Media New York 2013. [e-pub]

2012

  • Nuria Oliva, Sagi Shitreet, Eytan Abraham, Butch Stanley, Elazer R. Edelman, and Natalie Artzi. Natural Tissue Microenvironmental Conditions Modulate Adhesive Material Performance Langmuir, 2012, 28 (43), pp 15402–15409 [e-pub]
  • Nugent HM, Ng YS, White D, Groothius A, Kanner G, Edelman ER. Ultrasound-guided percutaneous delivery of tissue-engineered endothelial cells to the adventitia of stented arteries controls the response to vascular injury in a porcine model. J Vasc Surg. 2012 Oct;56(4):1078-88. doi: 10.1016/j.jvs.2012.03.002. 2012 Jul 15
  • Carlyle WC, McClain JB, Tzafriri AR, Bailey L, Zani BG, Markham PM, Stanley JR, Edelman ER. Enhanced Drug Delivery Capabilities from Stents Coated with Absorbable Polymer and Crystalline DrugJournal of controlled release : official journal of the Controlled Release Society. 2012 Jul 13.
  • Indolfi L, Baker AB, Edelman ER. The role of scaffold microarchitecture in engineering endothelial cell immunomodulationBiomaterials.2012 Jul 12.
  • Nugent HM, Ng YS, White D, Groothius A, Kanner G, Edelman ER. Ultrasound-guided, percutaneous delivery of tissue-engineered endothelial cells to the adventitia of stented arteries controls the response to vascular injury in a porcine modelJournal of Vascular Surgery. 2012 Jul 13.
  • Tzafriri AR, Groothuis A, Price GS, Edelman ER. Stent elution rate determines drug deposition and receptor-mediated effects. Journal of controlled release : official journal of the Controlled Release Society. 2012 May 26;161(3):918-926.
  • Baker AB, Gibson WJ, Kolachalama VB, Golomb M, Indolfi L, Spruell C, Zcharia E, Vlodavsky I, Edelman ER. Heparanase regulates thrombosis in vascular injury and stent-induced flow disturbanceJournal of the American College of Cardiology. 2012 Apr 24;59(17):1551-60. 22516446
  • Martorell J, Santomá P, Molins JJ, García-Granada AA, Bea JA, Edelman ER, Balcells M. Engineered arterial models to correlate blood flowAnnals of The New York Academy of Sciences. 2012 Apr;1254:51-6.
  • Edelman ER, LaMarco K. Clinician-investigators as translational bioscientists: shaping a seamless identity. Science Translational Medicine. 2012;4(135):135fs14
  • Shazly T, Kolachalama VB, Ferdous J, Oberhauser JP, Hossainy S, Edelman ER. Assessment of material by-product fate from bioresorbable vascular scaffoldsAnnals of biomedical engineering. 2012;40(4):955-65.
  • Jang E, Albadawi H, Watkins MT, Edelman ER, Baker AB. Syndecan-4 proteoliposomes enhance fibroblast growth factor-2 (FGF-2)-induced proliferation, migration, and neovascularization of ischemic muscleProceedings of the National Academy of Sciences of the United States of America. 2012;109(5):1679-84.
  • Aronson D, Edelman ER. Role of CABG in the management of obstructive coronary arterial disease in patients with diabetes mellitus.Current opinion in pharmacology.

2011

  • Franses JW, Edelman ER. The evolution of endothelial regulatory paradigms in cancer biology and vascular repairCancer research. 2011;71(24):7339-44.
  • Balcells M, Edelman ER. Models of human vascular disease: is there an animal of la mancha?Revista espanola de cardiologia. 2011;64(9):739-42.
  • Edelman, ER, FitzGerald, GA. A rattle bag of science and the art of translationScience Translational Medicine 2011 Oct; (3)104:104ed3.
  • Lovich M, Wei A, Wu P, Maslov M, Edelman ER. Local epicardial inotropic drug delivery allows targeted pharmacologic intervention with preservation of myocardial loading conditionsJournal of Pharmaecutical Sciences 2011 Nov;100(11):4993-5006.
  • Chitalia V, Murikipudi S, Indolfi L, Rabadi L, Valdez R, Franses J, Edelman ER. Matrix-embedded endothelial cells are protected from the uremic milieuNephrology Dialysis Transplantation 2011 July; 0:1-8. [PDF]
  • Artzi N, Oliva N, Puron C, Shitreet S, Artzi S, Bon Ramos A, Groothuis A, Sahagian G, Edelman ER. In vivo and in vitro tracking of erosion in biodegradable materials using non-invasive fluorescence imagingNature Materials 2011 Sep; 10(9):704-709.
  • Kolandaivelu K, Swaminathan R, Gibson W, Kolachalama V, Nguyen-Ehrenreich KL, Giddings V, Coleman L, Wong G, Edelman ER. Stent thrombogenicity early in high-rish interventional settings is driven by stent design and deployment and proteced by polymer-drug coatingsCirculation 2011 Apr; 123(13): 1400-1409.
  • Schubert S, Benarroch A, Monter-Solans J, Edelman ER. Primary monocytes regulate endothelial cell survival through secretion of angiopoietin-1 and activation of endothelial Tie2Arteriosclerosis Thrombosis and Vascular Biology 2011 Apr; 31(4): 870-875.
  • Chatzizisis Y, Baker A, Sukhova G, Koskinas K, Papafaklis M, Beigel R, Jonas M, Coskun A, Stone B, Maynard C, Shi GP, Libby P, Feldman C, Edelman ER, Stone P. Augmented expression and activity of extracellular matrix-degrading enzymes in regions of low endothelial shear stress co-localize with coronary atheromata with thin fibrous caps in pigsCirculation 2011 Feb; 123(6): 621-630.
  • Franses JW, Baker AB, Chitalia VC, Edelman ER. Stromal endothelial cells directly influence cancer progressionScience Translational Medicine 2011 Jan; 66(3):66ra5.
  • Artzi N, Zeiger A, Boehning F, Bon Ramos A, Van Vliet K, Edelman ER. Tuning adhesion failure strength for tissue-specific applications.Acta Biomaterialia 2011 Jan; 7(1): 67-74.

2010

  • Baker A, Chatzizisis Y, Beigel R, Jonas M, Stone B, Coskun A, Maynard C, Rogers C, Koskinas K, Feldman C, Stone P, Edelman ER.Regulation of heparanase expression in coronary artery disease in diabetic hyperlipidemic swineAtherosclerosis 2010 Dec; 213(2):436-442.
  • Shazly T, Baker A, Naber J, Bon A, Van Vliet K, Edelman ER. Augumentation of postswelling surgical sealant potential of adhesive hydrogelsJournal of Biomedical Materials Resources A 2010 Sept; 95(4):1159-69.
  • Balcells M, Martorell J, Olive C, Santacana M, Chitalia V, Cardoso A, Edelman ER. Smooth muscle cells orchestrate the endothelial cell response to flow and injuryCirculation 2010 May; 121(20): 2192-9.
  • Zani BG and Edelman ER. Cellular bridges: routes for intercellular communication and cell migrationCommunicative and Integrative Biology 3:3, 1-6; May/June 2010.
  • Koskinas K, Feldman C, Chatzizisis Y, Coskun A, Jonas M, Maynard C, Baker A, Papafaklis M, Edelman ER, Stone P. Natural History of Experimental Coronary Atherosclerosis and Vascular Remodeling in Relation to Endothelial Shear Stress. A Serial, In Vivo Intravascular Ultrasound StudyCirculation 2010 May; 121(19):2092-101.
  • Brown L, Edelman ER. Optimal control of blood glucose: the diabetic patient or the machinewww. Science Translation Medicine.org2010 Apr;27(2): 27ps18.
  • Methe H, Nanasato M, Spognardi A, Groothuis A, Edelman ER. T-helper 2 cells are essential for modulation of vascular repair by allogeneic endothelial cellsJournal of Heart and Lung Transplantation 2010 Apr; 29(4):479-486
  • Aronson D, Edelman ER. Revascularization for coronary artery disease in diabetes mellitus: Angioplasty, stents and coronary artery bypass graftingReviews in Endocrine and Metabolic Disorders 2010 Mar; 11(1): 75-86.
  • Tzafriri A, Vukmirovic N, Kolachalama V, Astafieve I, Edelman ER. Lesion complexity determines arterial drug distribution after local drug deliveryJournal of Controlled Release 2010 Mar;142(3): 332-338.
  • Schubert SY, Benarroch A, Monter-Solans J, Edelman ER. Monocyte activation state regulates monocyte-induced endothelial proliferation through Met signalingBlood 2010 Apr;115(16):3407-3412.
  • Zani BG, Indolfi L, Edelman ER. Tubular bridges for bronchial epithelial cell migration and communicationPloS ONE 2010 Jan; 5(1): e8930.

2009

  • Kolachalama VB, Levine EG, Edelman ER. Luminal flow amplifies stent-based drug deposition in arterial bifurcationsPloS ONE 2009 Dec; 4(12): e8105.
  • Nugent HM, Ng YS, White D, Groothius A, Kanner G, Edelman ER. Delivery Site of Perivascular Endothelial Cell Matrices Determines Control of Stenosis in a Porcine Femoral Stent ModelJournal of Vascular Intervention in Radiology 2009 Dec; 20(12):1617-24.
  • Koskinas, KC, Chatzizisis YS, Baker AB, Edelman ER, Stone PH, Feldman CL. The role of low endothelial shear stress in the conversion of atherosclerotic lesions from stable to unstable plaqueCurrent Opinion in Cardiology 2009 Oct; 24(6):580-90.
  • Artzi N, Shazly T, Crespo C, Bon Ramos A, Chenault K, Edelman ER. Characterization of star adhesive sealant based on PEG:dextran hydrogelsMacromolecular Bioscience 2009 Aug;9(8):754-65.
  • Artzi N*, Shazly T*, Baker A, Bon A, Edelman ER. Aldehyde-Amine Chemistry Enables Modulated Biosealants with Tissue-Specific AdhesionAdvanced Materials 2009; 21:3399-3403.*Indicates equal author contribution
  • Mobine H, Baker A, Wang L, Wakimoto H, Jacobsen K, Seidman C, Seidman J, Edelman ER. Pheochromocytoma-Induced Cardiomyopathy is Modulated by the Synergistic Effects of Cell-Secreted FactorsCirc Heart Fail 2009:1-16.
  • Wu PI, Minisini S, Edelman ER. Intramuscular drug transport under mechanical loading: resonance between tissue function and uptake.J Control Release 2009; 136(2): 99-109.
  • Morss Clyne A, Edelman ER. Vascular growth factor binding kinetics to the endothelial cell basement membrane, with a kinetics-based correction for substrate bindingCytotechnology 2009 Jul; 60(1): 33-44.
  • Mobine H, Engelmayr G, Moussazadeh N, Anwar T, Freed L, Edelman ER. Encapsulated pheochromocytoma cells secrete potent non-catecholamine factorsTissue Engineering Part A 2009 Jul;15(7):1719-28.
  • Hess S, Methe H, Kim JO, Edelman ER. NF-kappaB activity in endothelial cells is modulated by cell substratum interactions and influences chemokine-mediated adhesion of natural killerCell Transplantation 2009 18(3): 261-73.
  • Alexander I, Edelman ER, Methe H. Function and mode of regulation of endothelial major histocompatibility complex class IICell Transplantation 2009; 18(3):255-259.
  • Tzafriri AR, Levin AD, Edelman ER. Diffusion-limited binding explains binary dose response for local arterial and tumor drug delivery.Cell Proliferation 2009 42(3): 348-363.
  • Le KN, Hwang CW, Tzafriri A, Lovich MA, Hayward A, Edelman ER. Vascular regeneration by local growth factor release is self-limited by microvascular clearance. Circulation 2009;119(22):2928-2935.
  • Maron B, Kolandaivelu K, Rhee D, Bukhman A, Edelman ER. Echocardiographic capture of right ventricular wall rupture during inferior wall acute myocardial infarctionAmerican Journal of Cardiology 2009 May;103(10):1478-1480.
  • Chatzizisis YS, Jonas M, Beigel R, Coskun A, Baker AB, Stone BV, Maynard C, Gerrity RG, Daley W, Edelman ER, Feldman CL, Stone PH.Attenuation of inflammation and expansive remodeling by Valsartan alone or in combination with Simvastatin in high-risk coronary atherosclerotic plaquesAtherosclerosis 2009; 203:387-394.
  • Baker AB, Groothuis A, Jonas M, Ettenson DS, Shazly T, Zcharia E, Vlodavsky I, Seifert P, Edelman ER. Heparanase alters arterial structure, mechanics, and repair following endovascular stenting in miceCirculation Research 2009 Feb;104(3):380-387.
  • Kolachalama VB, Tzafriri AR, Arifin DY, Edelman ER. Luminal flow patterns dictate arterial drug deposition in stent-based deliveryJ Control Release 2009 Jan; 133(1):24-30.

2008

  • Shazly TM, Artzi N, Boehning F, Edelman ER. Viscoelastic adhesive mechanics of aldehyde-mediated soft tissue sealantsBiomaterials2008 Dec; 29(35): 4584-4591.
  • Balakrishnan B, Dooley J, Kopia G, Edelman ER. Thrombus causes fluctuations in arterial drug delivery from intravascular stentsJ Control Release 2008 Nov; 131(3):173-180.
  • Danenberg H, Grad E, Swaminathan RV, Chen Z, Seifert P, Szalai AJ, Lotan C, Simon DI, Edelman ER. Neointimal formation is reduced after arterial injury in human crp transgenic miceAtherosclerosis 2008 Nov; 201(1):85-91.
  • Wu P, Edelman ER. Structural biomechanics modulate intramuscular distribution of locally delivered drugsJ Biomech 2008 41(13):2884-2891.
  • Clyne-Morss A, Zhu H, Edelman ER. Elevated fibroblast growth factor-2 increases tumor necrosis factor-α induced endothelial cell death in high glucoseJ Cell Physiol 2008 Oct; 217(1): 86-92.
  • Baker A, Ettenson D, Jonas M, Nugent M, Iozzo R, Edelman ER. Endothelial cells provide feedback control for vascular remodeling through mechanosensitive autocrine TGF2-beta signaling pathwayCirc Res 2008 Aug;103(3);289-297.
  • Mi LY, Ettenson D, Edelman ER. Phospholipase C-delta extends intercellular signalling range and responses to injury-released growth factors in non-excitable cellsCell Prolif 2008 Aug;41(4):671-690.
  • Epstein H, Grad E, Golomb M, Koroukhov N, Edelman ER, Golomb G, Danenberg H. Innate immunity has a dual effect on vascular healing: Suppression and aggravation of neointimal formation and remodeling postendotoxin challengeAtherosclerosis 2008 Jul; 199(1):41-46.
  • Balcells M, Wallins J, Edelman ER. Amyloid beta toxicity dependent upon endothelial cell stateNeuroscience Letters 2008 Aug; 441(3):319-322.
  • Zani BG, Kojima K, Vacanti CA, and Edelman ER. Tissue engineered endothelial and epithelial implants differentially and synergistically regulate airway repair. Proc Natl Acad Sci U S A. 2008 May 13; 105(19): 7046-7051. Epub 2008 May 5.
  • Methe H, Hess S, Edelman ER. The effect of three-dimensional matrix-embeding of endothelial cells on the humoral and cellular immune response. Seminars in Immunology 2008 Apr; 20(2):117-122.
  • Chatzizisis YS, Jonas M, Coskun AU, Beigel R, Stone BV, Maynard C, Gerrity RG, Daley W, Rogers C, Edelman ER, Feldman CL, Stone PH.Prediction of the localization of high-risk coronary atherosclerotic plaques on the basis of low endothelial shear stress. An intravascular ultrasound and histopathology natural history study. Circulation 2008 Feb;117:993-1002.
  • Schubert SY, Benarroch A, Ostvang J, Edelman ER. Regulation of endothelial cell proliferation by primary monocytes. Arterioscler Thromb Vasc Biol 2008 Jan; 28(1): 97-104.
  • Schwartz RS, Edelman ER, Virmani R, Carter A, Granada JF, Kaluza GL, Chronos N, Robinson KA, Waksman R, Weinberger J, Wilson GJ, Wilensky RL. Drug-Eluting Stents in Preclinical Studies: Updated Consensus Recommendations for Preclinical Evaluation. Circ Cardiovasc Intervent 2008; 1:143-153.

2007

  • Balakrishnan B, Dooley J, Kopia G, Edelman ER. Intravascular drug release kinetics dictate arterial drug deposition, retention, and distribution. J Control Release 2007; 123(2): 100-108.
  • Chatzizisis YS, Coskun AU, Jonas M, Edelman ER, Stone PH, Feldman CL. Risk stratification of individual coronary lesions using local endothelial shear stress: a new paradigm for managing coronary artery diseaseCurr Opin Cardiol 2007; 22(6):552-564.
  • Methe H, Hess S, Edelman ER. Endothelial immunogenicity — A matter of matrix microarchitectureThromb Haemost 2007; 98(2):278-82.
  • Nugent HM, Sjin RT, White D, Milton LG, Manson RJ, Lawson JH, Edelman ER. Adventitial endothelial implants reduce matrix metalloproteinase-2 expression and increase luminal diameter in porcine arteriovenous graftsJ Vasc Surg 2007 Sept; 46(3):548-556.
  • Grad E, Golomb M, Mor Yosef I, Koroukhov N, Lotan C, Edelman ER, Danenberg HD. Transgenic expression of human C-reactive protein suppresses endothelial nitric oxide synthase expression and bioactivity folllowing vascular injuryAm J Physiol Heart Circ Physiol2007 Jul; 293(1): H489-95.
  • Chatzizisis YS, Coskun AU, Jonas M, Edelman ER, Feldman CL, Stone PH. Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: Molecular, cellular and vascular behaviorJ Am Coll Cardiol 2007 Jun 26; 49(25): 2379-2393.
  • Methe H, Hess S, Edelman ER. Endothelial cell-matrix interactions determine maturation of dendritic cellsEur J Immunol 2007 Jun 11; 37(7):1773-1784.
  • Morss AS, Edelman ER. Glucose modulates basement membrane fibroblast growth factor-2 via alternations in endothelial cell permeabilityJ Biol Chem 2007 May;282(19):14635-14644.
  • Methe H. Balcells M, Alegret MD, Santacana M, Molins B, Hamik A, Jain M, Edelman ER. Vascular bed origin dictates flow pattern regulation of endothelial adhesion molecule expressionAm J Physiol Heart Circ Physiol 2007 May; 292(5):H2167-2175.
  • Tzafriri AR, Edelman ER. Quasi-steady state kinetics at enzyme and substrate concentrations in excess of the Michaelis-Menten contstantJ Theor Biol 2007 Apr; 245(4): 737-48.
  • Tzafriri AR, Edelman ER. Endosomal receptor kinetics determine the stability of intracellular growth factor signaling complexes.Biochem J 2007, Mar 15;402(3):537-549.
  • Hamik A, Lin Z, Kumar A, Balcells M, Sinha S, Katz J, Feinberg M, Gerzsten R, Edelman ER, Jain M. Kruppel-like factor 4 regulates endothelial inflammationJ Biol Chem 2007 May, 28(18):13769-79.
  • Thomas A, Edelman ER, Stultz CM. Collagen fragments modulate innate immunityExp Biol Med 2007 Mar; 232(3):406-411.
  • Danenberg HD, Kantak N, Grad E, Swaminathan RV, Lotan C, Edelman ER. C-reactive protein promotes monocyte-platelet aggregation: an additional link to the inflammatory-thrombotic intricacyEur J Haematol 2007 Mar;78(3):246-252.
  • Methe H, Groothuis A, Sayegh MH, Edelman ER. Matrix adherence of endothelial cells attenuates immune reactivity: induction of hyporesponsiveness in allo- and xenogeneic modelsFaseb J 2007 Jan; 21(7):1515-26.

2006

  • Methe H, Edelman ER. Tissue engineering of endothelial cells and the immune responseTransplant Proc 2006 Dec.; 38(10):3293-3299.
  • Methe, H, Edelman ER. Cell-matrix contact prevents recognition and damage of endothelial cells in states of heightened immunity.Circulation 2006 July 4; 114:I-233-I-238.
  • Richter Y, Edelman, ER. Cardiology Is Flow. Circulation 2006 June 13;113:2679-2682.
  • Rogers C, Edelman ER. Pushing Drug-Eluting Stents Into Uncharted Territory. Simpler Than You Think–More Complex Than You ImagineCirculation 2006 May 16; 113:2262-2265.
  • Costa LF, Balcells M, Edelman ER, Nadler LM, Cardoso AA. Proangiogenic stimulation of bone marrow endothelium engages mTOR and is inhibited by simultaneous blockage of mTOR and NF-(kappa)BBlood 2006 107(1): 285-292.

 


2005

  • Levin AD, Jonas M, Hwang CW, Edelman ER. Local and systematic drug competition in drug-eluting stent tissue deposition propertiesJ Control Release 2005 Aug 15;109:236-243.
  • Methe H, Nugent HM, Groothuis A, Seifert P, Sayegh MH, Edelman, ER. Matrix Embedding Alters the Immune Response Against Endothelial Cells In Vitro and In VivoCirculation 2005 Aug 30;112:189-195.
  • M Jonas M, Edelman ER, Groothuis A, Baker AB, Seifert P, Rogers C. Vascular neointimal formation and signaling pathway activation in response to stent injury in insulin-resistant and diabetic animals. Circ Res 2005 Sep 30;97(7):725-33. Epub 2005 Aug 25
  • Methe H, Brunner S, Wiegand D, Nabauer M, Koglin J, Edelman ER. Enhanced T-Helper-1 Lymphocyte Activation Patterns in Acute Coronary Syndromes. J Am Coll Cardiol 2005 Jun 21;45(12):1939-1945.
  • Balakrishnan B, Tzafriri AR, Seifert P, Groothuis A, Rogers C, Edelman ER. Strut position, blood flow, and drug deposition: implications for single and overlapping drug-eluting stents. Circulation 2005 Jun 7;111(22):2958-65.
  • Hwang CW, Levin AD, Jonas M, Li PH, Edelman ER. Thrombosis modulates arterial drug distribution for drug-eluting stents. Circulation2005 Apr 5;111(13):1619-26.
  • Tzafriri AR , Edelman ER. On the validity of the quasi-steady state approximation of bimolecular reactions in solution. J Theor Biol 2005 Apr 7;233(2):343-350.
  • Balcells M, Fernandez MS, Vazquez M, Edelman ER. Cells in Fluidic Environments are Sensitive to Flow FrequencyJ Cell Physiol 2005 Feb 7; 204: 329-335.

2004

  • Schwartz RS, Edelman ER, Carter A, Chronos NA, Rogers C, Robinson KA, Waksman R, Machan L,Weinberger J, Wilensky RL, Goode JL, Hottenstein OD, Zuckerman BD, Virmani R. Preclinical evaluation of drug-eluting stents for peripheral applications: recommendations from an expert consensus group. Circulation 2004 Oct 19;110(16):2498-505.
  • Kolandaivelu K, Edelman ER. Environmental influences on endovascular stent platelet reactivity: An in vitro comparison of stainless steel and gold surfaces. Journal of Biomedical Materials Research 2004 Aug 1;70A(2):186-93.
  • Levin AD, Vukmirovic N, Hwang CW, Edelman ER. Specific binding to intracellular proteins determines arterial transport properties for rapamycin and paclitaxel. Proceedings of the National Academy of Sciences USA. 2004 Jun 22;101(25):9463-7.
  • Richter Y, Groothuis A, Seifert P, Edelman ER. Dynamic flow alterations dictate leukocyte adhesion andresponse to endovascular interventionsJournal of Clinical Investigations. 2004 Jun;113(11):1607-14.
  • Tzafriri AR, Wu D, Edelman ER. Analysis of compartmental models of ligand-induced endocytosis Journal of Theoretical Biology. 2004 Jun 21; 229: 127-138.
  • Sapp JL, Cooper JM, Soejima K, Sorrell T, Lopera G, Satti SD, Koplan BA, Epstein LM, Edelman E, Rogers C, Stevenson WG. Deep Myocardial Ablation Lesions Can Be Created with a Retractable Needle-Tipped Catheter. Pacing Clin Electrophysiol. 2004 May;27(5):594-599.
  • Rogers C, Huynh R, Seifert PA, Chevalier B, Schofer J, Edelman ER, Toegel G, Kuchela A, Woupio A, Kuntz RE, Macon ND. Embolic protection with filtering or occlusion balloons during saphenous vein graft stenting retrieves identical volumes and sizes of particulate debris. Circulation. 2004 Apr13;109(14):1735-40.
  • Wu D, Edelman ER. Resonance Energy Transfer for Assessing the Molecular Integrity of Proteins for Local Delivery. Biotechnology and Bioengineering. 2004 Feb 20; 85(4): 406-412.
  • Tzafriri AR, Edelman ER. The Total Quasi-Steady State Approximation is Valid for Reversible Enzyme Kinetics Journal of Theoretical Biology. 2004 Feb 7; 226: 301-311.

2003

  • Danenberg HD, Golomb G, Groothuis A, Gao J, Epstein H, Swaminathan RV, Seifert P, Edelman ER. Liposomal Alendronate Inhibits Systemic Innate Immunity and Reduces In-Stent NeointimalHyperplasia in Rabbits. Circulation. 2003 Dec 2; 108(22):2798-2804.
  • Janicki C, Hwang CW, Edelman ER. Dose model for stent-based delivery of a radioactive compound for the treatment of restenosis in coronary arteries. Medical Physics. 2003 Oct; 30(10): 2622-2628.
  • Stultz CM, Edelman ER. A structural model that explains the effects of hyperglycemia on collagenolysis. Biophysical Journal. 2003 Oct; 85(4):2198-2204.
  • Danenberg HD, Szalai AJ, Swaminathan RV, Peng L, Chen Z, Seifert P, Fay WP, Simon DI, Edelman ER. Increased thrombosis after arterial injury in human C-reactive protein-transgenic mice. Circulation. 2003 Aug 5;108(5):512-5.
  • Welt FG, Tso C, Edelman ER, Kjelsberg MA, Paolini JF, Seifert P, Rogers C. Leukocyte recruitment and expression of chemokines following different forms of vascular injury. Vascular Medicine. 2003;8(1):17.
  • Edelman ER, Danenberg HD. Rapamycin for cardiac transplant rejection and vasculopathy: one stone, two birds? Circulation. 2003 Jul 8;108(1):6-8.
  • Nugent HM, Edelman ER. Tissue engineering therapy for cardiovascular disease. Circulation Research. 2003 May 30;92(10):1068-78.
  • Hwang CW, Wu D, Edelman ER. Impact of transport and drug properties on the local pharmacology of drug-eluting stents. International Journal of Cardiovascular Interventions. 2003;5(1):7-12.

2002

  • Kolandaivelu K, Edelman ER. Low background, pulsatile, in vitro flow circuit for modeling coronary implant thrombosis. Journal of Biomechanical Engineering.2002 Dec;124(6):662-8.
  • Nugent HM, Groothuis A, Seifert P, Guerraro JL, Nedelman M, Mohanakumar T, Edelman ER. Perivascular endothelial implants inhibit intimal hyperplasia in a model of arteriovenous fistulae: a safety and efficacy study in the pig. Journal of Vascular Research. 2002 Nov-Dec;39(6):524-33.
  • Stultz CM, Levin AD, Edelman ER. Phosphorylation-induced conformational changes in a mitogen-activated protein kinase substrate. Implications for tyrosine hydroxylase activation. Journal of Biological Chemistry. 2002 Dec 6;277(49):47653-61.
  • Welt FG, Rogers C. Inflammation and restenosis in the stent era. Arteriosclerosis, Thrombosis and Vascular Biology. 2002 Nov 1;22(11):1769-76.
  • Schwartz RS, Edelman ER, Carter A, Chronos N, Rogers C, Robinson KA, Waksman R, Weinberger J, Wilensky RL, Jensen DN, Zuckerman BD, Virmani R. Drug-eluting stents in preclinical studies: recommended evaluation from a consensus group.Circulation 2002 Oct 1;106(14):1867-73.
  • Lewis EF, Edelman ER. Acute ST depressions in a patient with idiopathic hypertrophic subaortic stenosis and normal coronary arteriesCirculation 2002 Aug 6;106(6):757-8.
  • Danenberg HD, Welt FG, Walker M 3rd, Seifert P, Toegel GS, Edelman ER. Systemic inflammation induced by lipopolysaccharide increases neointimal formation after balloon and stent injury in rabbitsCirculation. 2002 Jun 18. 105(24): 2917-22.
  • Balcells M, Edelman ER. Effect of Pre-Adsorbed Proteins on Attachment, Proliferation, and Function of Endothelial CellsJournal of Cellular Physiology. 2002 May. 191: 155-161.
  • Hwang CW, Edelman ER. Arterial ultrastructure influences transport of locally delivered drugsCirculation Research. 2002 Apr 19. 90(7): 826-832.
  • Welt FG, Horvath C, Nedelman M, Rao P, Rogers C. Targeting CCR2 or CD18 inhibits experimental in-stent restenosis in primates: inhibitory potential depends on type of injury and leukocytes targetedCirculation Research. 2002 Mar 8; 90(4): 488-94.
  • Woods TC, Blystone CR, Yoo J, Edelman ER. Activation of EphB2 and its ligands promote vascular smooth muscle cell proliferation.Journal of Biological Chemistry. 2002 Jan 18. 277(3): 1924-7.

2001

  • Welt FG, Woods TC, Edelman ER. Oral Heparin Prevents Neointimal Hyperplasia After Arterial Injury: Inhibitory Potential Depends on Type of Vascular InjuryCirculation. 2001 Dec 18. 104(25): 3121-3124.
  • Edelman ER. On Causes: Hippocrates, Aristotle, Robert Koch, and the Dread Pirate RobertsCirculation. 2001 Nov 20. 104(21): 2509-2512.
  • Lovich MA, Creel CJ, Hong K, Hwang CW, Edelman ER. Carrier proteins determine local pharmacokinetics and arterial distribution of paclitaxelJournal of Pharmaceutical Sciences. 2001 Sep. 90(9): 1324-1335.
  • Nugent HM, Edelman ER. Endothelial implants provide long-term control of vascular repair in a porcine model of arterial injuryJournal of Surgical Research. 2001 Aug. 99(2): 228-34.
  • Hwang CW, Wu D, Edelman ER. Physiological transport forces govern drug distribution for stent-based deliveryCirculation. 2001 Jul 31. 104(5): 600-605.
  • Consi TR, Seifert PA, Triantafyllou MS, Edelman ER. The dorsal fin engine of the seahorse (Hippocampus sp.)Journal of Morphology. 2001 Apr. 248(1): 80-97.
  • Edelman ER, Seifert P, Groothuis A, Morss A, Bornstein D, Rogers C. Gold-coated NIR stents in porcine coronary arteriesCirculation. 2001 Jan 23. 103(3): 429-434.

2000

  • Welt FG, Edelman ER, Simon DI, Rogers C. Neutrophil, not macrophage, infiltration precedes neointimal thickening in balloon-injured arteriesArteriosclerosis, Thrombosis and Vascular Biology. 2000 Dec; 20(12): 2553-2558.
  • Drachman DE, Edelman ER, Seifert P, Groothuis AR, Bornstein DA, Kamath KR, Palasis M, Yang D, Nott SH, Rogers C. Neointimal thickening after stent delivery of paclitaxel: change in composition and arrest of growth over six months. Journal of the American College of Cardiology. 2000 Dec;36(7): 2325-2332.
  • Edelman ER, Nathan A, Katada M, Gates J, Karnovsky MJ. Perivascular graft heparin delivery using biodegradable polymer wraps.Biomaterials. 2000 Nov; 21(22): 2279-2286.
  • Elmalak O, Lovich MA, Edelman E. Correlation of transarterial transport of various dextrans with their physicochemical properties.Biomaterials. 2000 Nov; 21(22): 2263-2272.
  • Parikh SA, Edelman ER. Endothelial cell delivery for cardiovascular therapyAdvanced Drug Delivery Reviews. 2000 Aug; 42(1-2): 139-161. Review.
  • Ettenson DS, Koo EW, Januzzi JL, Edelman ER. Endothelial heparan sulfate is necessary but not sufficient for control of vascular smooth muscle cell growthJ Cell Physiol 2000 Jul;184(1): 93-100.
  • Nugent MA, Nugent HM, Iozzo RV, Sanchack K, Edelman ER. Perlecan is required to inhibit thrombosis after deep vascular injury and contributes to endothelial cell-mediated inhibition of intimal hyperplasiaProceedings of the National Academy of Sciences U S A. 2000 Jun;97(12): 6722-6727.
  • Tavakkolizadeh A, Shen R, Abraham P, Kormi N, Seifert P, Edelman ER, Jacobs DO, Zinner MJ, Ashley SW, Whang EE. Glucagon-like peptide 2: a new treatment for chemotherapy-induced enteritisJournal of Surgical Research. 2000 Jun; 91(1): 77-82.
  • Creel CJ, Lovich MA, Edelman ER. Arterial paclitaxel distribution and depostionCirculation Research. 2000 Apr;86(8):879-884.
  • Garasic JM, Edelman ER, Squire JC, Seifert P, Williams MS, Rogers C. Stent and artery geometry determine intimal thickening independent of arterial injuryCirculation. 2000 Feb;101(7): 812-8.
  • Simon DI, Dhen Z, Seifert P, Edelman ER, Ballantyne CM, Rogers C. Decreased neointimal formation in Mac-1(-/-) mice reveals a role for inflammation in vascular repair after angioplastyJournal of Clinical Investigation. 2000 Feb;105(3): 293-300.
  • Noh I, Lovich MA, Edelman ER. Mechanisms of heparin transport through expanded poly(tetrafluoroethylene) vascular graftsJournal of Biomedical Materials Research. 2000 Jan;49(1): 112-9.

1999

  • Edelman ER. Vascular tissue engineering: designer arteriesCirc Res1999 Dec; 85(12): 1173-1178.
  • Laham RJ, Sellke FW, Edelman ER, Pearlman JD, Ware JA, Brown DL, Gold JP, Simons M. Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: results of a phase I randomized, double-blind, placebo-controlled trial.Circulation. 1999 Nov;100(18): 1865-71.
  • Squire JC, Rogers C, Edelman ER. Measuring arterial strain induced by endovascular stents. Med Biol Eng Comput. 1999 Nov; 37(6):692-8.
  • Lovich MA and Edelman ER. Tissue concentration of heparin, not administered dose, correlates with the biological response of injured arteries in vivoProc Natl Acad Sci U S A. 1999 Sep 28. 96: 11111-11116.
  • Edelman ER, Rogers C. Stent-versus-stent equivalency trials : are some stents more equal than others? Circulation. 1999 Aug; 100(9): 896-8.
  • Wan WK, Lovich MA, Hwang CW, Edelman ER. Measurement of drug distribution in vascular tissue using quantitative fluorescence microscopyJ Pharma Sci 1999 Aug; 88(8): 822-829.
  • Nugent HM, Rogers C, Edelman ER. Endothelial Implants Inhibit Intimal Hyperplasia After Porcine AngioplastyCirc Res 1999 Mar; 84(4): 384-391.
  • Rogers C, Tseng D, Squire JC, Edelman ER. Balloon-Artery Interactions During Stent Placement: A Finite Element Analysis Approach to Pressure, Compliance, and Stent Design as Contributors to Vascular InjuryCirc Res 1999 Mar; 84(4), 378-383.

Pre-1999

  • Rogers C, Edelman Er, Simon DI. A mAb to the β2–leukocyte integrin Mac-1 (CD11byCD18) reducesintimal thickening after angioplasty or stent implantation in rabbitsProc Natl Acad Sci USA 1998 Aug;95(17):10134-9.
  • Yu C, Cunningham M, Rogers c,Dinbergs ID, Edelman ER. The biologic effects of growth factor-toxin conjugates in models of vascular injury depend on dose, mode of delivery, and animal speciesJ Pharm Sci 1998 Nov;87(11):1300-4.
  • Sellke FW, Laham RJ, Edelman ER, Pearlman JD, Simons M. Therapeutic angiogenesis with basic fibroblast growth factor: Technique and early resultsAnn Thorac Surg 1998 Jun;65(6):1540-4.
  • Lovich MA, Brown LR, Edelman ER. Drug clearance and arterial uptake after local perivascular delivery to the rat carotid arteryJ Am Coll Cardiol 1997 Jun;29(7):1645-50.
  • Lopez JJ, Edelman ER, Stamler A, Hibberd MG, Prasad P, Caputo RP, Carrozza JP, Douglas PS, Sellke FW, Simons M. Basic fibroblast growth factor in a porcine model of chronic myocardial ischemia: a comparison of angiographic, echocardiographic and coronary flow parametersJ Pharmacol Exp Ther 1997 Jul; 282(1):385-90.
  • Brown LR, Edelman ER, Fischel-Ghodsian F, Langer RS. Characterization of glucose-mediated insulin release from implantable polymersJ Pharm Sci 1996 Dec; 85(12):1341-5.
  • Lovich MA, Edelman ER. Tissue average binding and equilibrium distribution: An example with heparin in arterial tissuesBiophys J1996 Mar; 70(3):1553-9.
  • Nathan A, Nugent MA, Edelman ER. Tissue engineered perivascular endothelial cell implants regulate vascular injuryProc Natl AcadSci USA 1995 Aug;92(18):8130-4.
  • Lovich MA, Edelman ER. Mechanisms of transmural heparin transport in the rat abdominal aorta after local vascular deliveryCirc Res1995 Dec;77(6):1143-50.